Every so often someone points at NanoBase™, cites a paper, and says a tri-domain carrier cannot exist. They are usually holding a real citation. Here is the part they miss: the papers are correct, and not one of them is about NanoBase™. Read them properly and they describe exactly why the architecture works.

In 1949, William Griffin published the Hydrophilic-Lipophilic Balance. Seventy-five years later, HLB still runs most of the cosmetic category — and it still does not account for surface charge, colloidal energy barriers, particle size, Ostwald ripening, or multi-carrier specificity. NanoBase™ was built to close those five gaps, simultaneously, on a single lecithin chassis.