NanoBase™ Rx: The Pharmacy Compounding Industry's Full Replacement for HLB Chemistry

NanoBase™ Rx is a pharmacy compounding excipient that combines a tri-domain nano-colloidal Architecture with a lyotropic liquid crystal matrix. Engineered at Pensive Beauty Labs. The three engineered nano-domains (lipophilic, hydrophilic, interfacial bridging) are designed to be organized within a biomimetic lamellar and bicontinuous cubic liquid crystal phase structure that matches the native liquid crystalline lamellar organization of stratum corneum intercellular lipids. Lamellar and cubic phase organization is a design target pending small angle scattering confirmation. Excipient only. No API supplied.

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Nano Delivery Science, Technical Review Pensive Beauty Nano Delivery Science, Technical Review Pensive Beauty

Why Most Skincare Actives Never Reach the Dermis

Conventional emulsions produce 1-100 µm carriers against a stratum corneum barrier with 10-50 nm intercellular spacing. NanoBase™, a tri-domain nano-colloidal Architecture engineered to a ~185 nm design target and DLS-characterised every batch, is designed to address all three HLB barriers at the formulation level.

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